: This gram-stained micrograph of a rectal smear specimen reveals the presence of diplococcal Neisseria gonorrhoeae bacteria CDC/ Joe Miller. The pathogen is almost exclusively sexually transmitted and can be found in the genital tract, pharynx, and rectum. Aside from causing infection in the lower genital tract, it can also cause conjunctivitis and severe disseminated infections especially if acquired congenitally. Gonorrhea is any manifestation of infection by N gonorrhoeae. Networks and groups within the genus Neisseria: analysis of argF, recA, rho and 16S rRNA from human Neisseria species. Neisseria gonorrhoeae is a gram-negative diplococcus bacterium that is closely related to other human Neisseria species. If acquired congenitally from an infected mother, the neonate can present with ophthalmia neonatorum, which left untreated can cause blindness. The treatment of N gonorrhoeae is important in the prevention of infertility, chronic pelvic pain, and ectopic pregnancy in women. The main treatment for uncomplicated gonorrhea is monotherapy with single-dose intramuscular ceftriaxone. The CDC has identified specific serious public health threats including extended spectrum beta-lactamases (ESBLs) and the organism Pseudomonas aeruginosa, and has labeled carbapenemase-resistant. High rates of antimicrobial resistance have been reported, and antibiotic treatment should be guided by local and national guidelines. Treatment of cUTIs has become increasingly complex due to the rising prevalence of multidrug-resistant (MDR) gram-negative bacteria. ![]() ![]() If left untreated, N gonorrhoeae can disseminate to areas of the body to cause skin and synovial infections rarer complications include meningitis, endocarditis, and perihepatic abscesses. Risk factors include multiple sex partners in recent months, known partner with gonorrhea, drug use, prior STI, and men who have sex with men. Men typically present with a urethral discharge women are often asymptomatic, but may have vaginal discharge. Gonorrhea infection is a common STI caused by Neisseria gonorrhoeae, a gram-negative diplococcus bacterium that is closely related to other human Neisseria species.
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